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University Hospital Erlangen

Resection margin and residual disease

Ohtake T, Abe R, Kimijima I,

et al.

Intraductal extension of

primary invasive breast carcinoma treated by breast-conserving

surgery. Computer graphic three-dimensional reconstruction

of the mammary duct-lobular systems.

Cancer

1995;76:

32–45.

APBI relevant summary of computer assisted tumor mapping:

1.

Distance of intraductal tumor extension:

22,7 mm for pts. <30 y.

14,3 mm for pts. 30-40 y.

6,7-7,7 mm for pts. >40 y.

2.

The average maximum distance of extension was 11.9 mm

.

(Patients 50 years of age had a maximum

extension of 8 mm.)

3.

In contrast to Holland’s study, the

mean tumor size

in this study was only

1.7 cm.

Target definition - BACKGROUND

Japanese point of view