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Multi-institutional study on target volume delineation variation

in breast radiotherapy in the presence of guidelines

van Mourik et al. Radiother Oncol 94:286-91. 2010

CT slices of 3 patients with delineated excision cavity contours of all 13 observers

13 radiation oncologists (observers), 8 patients

- even in the presence of delineation guidelines

considerable delineation variation

is

present (0.24 < SD < 1.22 cm)

- presence of clips or seroma

reduced interobserver variation

(0.24 < SD < 0.62 cm)