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Organ

Parameter

MIBT

IMRT

p

PTV/PTVeval

COIN

0.69

0.85

<0.05

ipsilateral breast

V90 (%)

11.1

20.3

<0.05

non-target breast

V90 (%)

3.6

4.8

<0.05

ipsilateral lung

MLD (%)

5.1

7.1

<0.05

MLD: mean lung dose

<

<

<

<

Multicatheter interstitial brachytherapy (MIBT)

vs. intensity modulated radiotherapy (IMRT)

Major et al. Radiother Oncol,

http://dx.doi.org/10.1016/j.radonc.2016.08.003