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3451 patients recruited between 2000 and 2012

Prepathology stratum (n=2298):

TARGIT 2.1% versus EBRT 1.1% (p=0.31)

PgR+ predictor of outcome

Postpathology stratum (n=1153):

TARGIT 5.4% versus EBRT 1.7% (p0.069)

Less non-breast cancer-deaths: 1.4% vs 3.5%

Vaidya JS et al, Health Tecnol Assess 2016