740-741 / 1674
University Hospital Erlangen
Breast conserving surgery, „low risk“ breast cancer
1.
Patients aged 40 years or older ,
2
. pTis or pT1–2a (lesions of
≤
3 cm diameter), pN0/pNmi and M0
3.
Clear resection margins of at least 2 mm in any direction L0, V0, no EIC
.
Stratification
Accelerated Partial Breast Irradiation
SOLE Multicatheter Brachytherapy
HDR: 8x 4.0 Gy, 7x 4.3 Gy
PDR: 0.6-0.8 Gy up to 50 Gy
Whole Breast Irradiation
(50 Gy + Boost 10 Gy)
n=633
n=551
April 2004 - July 2009, 1184 patients