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NTEs: Time to first moderate/marked clinician assessed NTE

18

Whole

N=674

Reduced

N=674

Partial

N=670

Number of patients with

moderate/marked events (%)

134

(20)

108

(16)

92

(14)

KM 5 year event-free

(95% CI)

72.1%

(66.0 - 77.3)

78.9%

(74.2 - 82.8)

80.9%

(75.8 - 85.0)

Hazard ratio

(95% CI)

0.77

(0.60, 0.99)

0.68

(0.52, 0.89)

Log rank p-value

p=0.042

p=0.004