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Conclusion, RAPID

3D CRT APBI increases rates of adverse cosmesis and late RT toxicity

compared with standard WBI

3D CRT APBI should not take place outside clinical trial

Randomized Trial of Accelerated Partial Breast Irradiation,

The RAPID trial

Strenghts

Randomised

This interim analysis reports the most robust data on cosmesis from a 3D CRT

APBI trial

Patients, nurses and doctors reported similar results

Limitations

Short follow up

Further studies are needed to identify characteristics in patients who are well

treated with 3D CRT APBI