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Conclusions

57

Non-inferiority for

Reduced dose

and

Partial breast

compared with

Whole breast

RT in terms of LR

LR rates very low across all groups

Moderate/marked normal tissue effects low across

all groups

Partial breast

reduces severity of overall breast

appearance and breast hardness (PROMs)

Benefit of

partial breast

in moderate/marked worst

adverse events (physician reported)