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Detection
St t l
Background
ruc ura
element
Functional
•
Relatively easy to detect
•
Presence or absence
•
Often qualitative
•
Cost‐effective
•
Relatively Not‐easy to detect
•
Active or inactive
•
Qualitative and quantitative
•
Expensive
•
Representative of BoNT intoxication
SMPR Key Points
•
Botulinum
neurotoxin type A
•
Subtypes A2‐A8;
degree of confidence
( dd
)
•
Field deployable
assay
•
Complexities in
detecting di‐chain
and complex toxins,
a ress in SMPR
•
Characterization of B‐
G
culture filtrates