Initial GTV
Initial GTV
CTV
LR
CTV
IR
CTV
HR
Initial GTV GTV
res
week 7
week 1 week 2 week 3 week 4 week 5 week 6
week 1 week 2 week 3 week 4 week 5 week 6
week 1 week 2 week 3 week 4 week 5 week 6 week 7
EBRT
Chemotherapy
Brachy
PTV
-45
Initial
GTV-T
CTV-
N
LR
CTV-T
IMRT + IGRT
RChTh + BT in < 50 days
Small pelvis
Large pelvis
+ Para-aortic
Nodal
CTV-E based on Risk Group
Residual GTV-T, Adaptive HR CTV-T, IR CTV-T
High Risk
Intermediate
Risk
Low
Risk
CT
V-E
Initial
HR
CTV-T
EMBRACE II
www.embracestudy.dk