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Initial GTV

Initial GTV

CTV

LR

CTV

IR

CTV

HR

Initial GTV GTV

res

week 7

week 1 week 2 week 3 week 4 week 5 week 6

week 1 week 2 week 3 week 4 week 5 week 6

week 1 week 2 week 3 week 4 week 5 week 6 week 7

EBRT

Chemotherapy

Brachy

PTV

-45

Initial

GTV-T

CTV-

N

LR

CTV-T

IMRT + IGRT

RChTh + BT in < 50 days

Small pelvis

Large pelvis

+ Para-aortic

Nodal

CTV-E based on Risk Group

Residual GTV-T, Adaptive HR CTV-T, IR CTV-T

High Risk

Intermediate

Risk

Low

Risk

CT

V-E

Initial

HR

CTV-T

EMBRACE II

www.embracestudy.dk