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Dose planning and reporting for 3D image based
APBI (GEC-ESTRO trial)
planning aim: PD = 30.1Gy (7x 4.3Gy),
V
100
= 90%,
DNR <0.35,
implant-rib distance ≥ 5mm
Major et al. 2007, Radiother Oncol 90(1):48-55
Results for 28 pts. (mean and ranges):
volume PTV:
63.1cm³ (17.2-124cm³)
D
90
PTV:
102 % (99-107 %)
D
100
PTV::
69 % (90-96 %)
DNR:
0.33 (0.25-0.41)
skin D
max
:
53 % (18-75 %)
ipsilateral lung D
max
: 42 % (7-75 %)
V5Gy: 42.6 cm³ (0-160 cm³)
V10Gy: 4.8 cm³ (0-39.5 cm³)
V15Gy: 0.5 cm³ (0-7.9 cm³)
heart D
max
:
21 % (4-40 %)
V5Gy: 8 cm³ (0-33.5 cm³)
V10Gy: 0.1 cm³ (0-0.3 cm³)
PTV: excision cavity + 20mm safety margin
D
max
skin
≥5mm
lung
heart