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Guide to Expression of Uncertainty in Measurement

ISO GUM (2010)

precision ≠ accuracy

Type A (statistical: standard deviation of results)

Type B (non-Type A uncertainties)

Law of Propagation of Uncertainty (no covariations)

TG-138 applies principles for expressing brachytherapy

dosimetric uncertainties

expanded uncertainty,

k

= 2 (95.45% confidence, 21/22)

special case for large # DOF

k

= t-factor otherwise with covariations

Methodology for Uncertainty Estimation

DeWerd, et al,

Med. Phys.

38, 782-801 (2011)