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Baumann M. et al. Radiot Oncol 2011;100

Standard arm: 66 Gy/33 fr.

Experimental arm: 60 Gy/40 fractions, 3 fractions per day (weekend-less)

N.B. not all patients received neoadjuvant chemotherapy before RT

“Outcome after CHARTWEL or conventional fractionation was not different”

Hyperfractionated-accelerated RT