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QoL evaluated with the

FACT-LCS

scale

(Fuctional Assessment of Cancer Therapy

– Lung Cancer Subscale) at baseline (313

pts), 3 (219 pts) and 12 months (137 pts)

Significantly

more patients

on

74Gy

arm

had clinically meaningful

decline

in FACT-LCS at 3 months than on the

60Gy arm (45% vs. 30%, p=0.02)

At 12 months,

fewer patients

who

received

IMRT

(vs 3DCRT) had

clinically meaningful

decline

in FACT-

LCS (21% vs 46%, p=0.003)

FACT-LCS decline

Movsas B. et al., JAMA Oncol 2016;2

Impact of IMRT compared to 3D-CRT:

Quality of Life