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AXL-Axis: Additional Modes of Action
AXL immunosuppresses innate immune cells
AXL is expressed in immunosuppressive cells
AXL drives immunosuppressive cytokine release
AXL expression inhibits NK cell mediated anti-metastatic effects
AXL promotes vasculogenesis
AXL is overexpressed in EGFR-treatment resistant tumors
(Several Met inhibitors inhibit AXL)