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In the Era of Combined Modality therapy

Bigger is not Better (Radiation Fields)

Milan Trial

Bonadonna et al. J Clin Oncol 2004; 22(14):2835-2841

EORTC H8

Ferme et al. N Engl J Med.

2007; 357(19):1916-

1927

GHSG HD8

Engert et al. J Clin Oncol 2003; 21(19):3601-3608