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5.002 patients treated for HL with supradiaphragmatic RT at age <36 in UK

1956-2003

Median RT dose 36 Gy

Cumulative

risk at 40 years was 48%

for patients treated at

younger ages

with doses >40 Gy

Breast cancer

risk

was

twice as great

in patients treated with

mantle RT

as in those who received

different fields of supradiaphragmatic RT

Swerdlow AJ. et al. JCO 2012