5.002 patients treated for HL with supradiaphragmatic RT at age <36 in UK
1956-2003
Median RT dose 36 Gy
Cumulative
risk at 40 years was 48%
for patients treated at
younger ages
with doses >40 Gy
Breast cancer
risk
was
twice as great
in patients treated with
mantle RT
as in those who received
different fields of supradiaphragmatic RT
Swerdlow AJ. et al. JCO 2012