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Risk group

Histology

Adjuvant treatment

Low

Ia, G1-2, LVSI -ve None

Intermediate Ib, G1-2, LVSI -ve BT or none if <60

With LND

No LND

High-

intermediate

Ib, G1-2, LVSI +ve

Ia, G3

BT or none BT if G3 and LVSI -

EBRT if LVSI+

Colombo N. Radiother Oncol. 2015;117(3):559-81

ESMO-ESGO-ESTRO recommendations 2015

4 risk groups

LVSI must be unequivocally positive (not focal)