1766 / 1851
Regimens Number
of
patients
G3/G4
toxicity
Diarrhea
Interval to
surgery
(median in
days)
ypN+
pCR TRG0-1
De Gramont
RT 46-
50.4Gy
165
7.7% 53
19.9% 14% 49%
FOLFOX
RT 46-
50.4Gy
165
14.5% 52
12.6% 27.5% 68.5%
FOLFOX
alone
165
7.3% Not stated 26.5% 6.6% 32.9%