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R
ChemoRadiotherapy
then Surgery (143 pts)
Immediate Surgery (139 pts)
Chemoradiotherapy before surgery
Bosset et al., N Engl J Med, 1997; 337: 161-7
Radioth.: 5 x 3.7 Gy - 2 weeks - 5 x 3.7 Gy ( 37 Gy)
Chemoth.: Cisplatin (80 mg/m2) before RT
Stages: T1NO: 17%; T2N0: 33%;
T3N0: 27%
T1-T2 N1: 23%