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SWOG 7897

268 patients - IA2, IB, IIA

Radical hysterectomy + PLND

RT to pelvis (49.3 Gy in 29#) for

Positive LN

Positive margins

Parametrial disease

4 cycles of cisplatin 70 mg/m

2

+ 5-FU 1000 mg/m

2

/d x 4 days

Peters, et al. JCO 2000;

18

:1606-13