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Author
Patients
(n)
Results
Grabenbauer
38
CD3/CD4: decreased 3 years NED
Rubio
277
CD3/CD8: increased 15 years survival
Hu
40
intratumoral CD8: increased DFS
peritumoral CD8: increased OS
Gilbert
153
increased relapse-free survival
Prognostic relevance of TILs
Grabenbauer G, Clin Cancer Res 2006; Rubio C, Int J Clin Exp Pathol 2008; Hu W, J Surg Oncol. 2015; Gilbert DC, Br J C
High levels of TILs, especially CD8(+) cells,
are associated
with a favourable clinical response and survival