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ACT II Trial Design

n=940 - Recruitment 2001-2008

MMC

5FU 50.4Gy

MMC

5FU 50.4Gy

CisP

5FU 50.4Gy

CisP

5FU 50.4Gy

CisP 5FU x 2

CisP 5FU x 2

Arm 1

Arm 2

Arm 3

Arm 4

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