980 / 1851
Induction CT: CALGB 39801 – Trial Design
R
E
G
I
S
T
E
R
A (Concurrent
Chemo/RT)
B (Induction
Concurrent
Chemo/RT)
Paclitaxel 50 mg/m
2
IV/1h/week
Carboplatin AUC 2 IV/30 min/wk
XRT 6600 cGy (total)
Paclitaxel 200 mg/m
2
IV/3h
Carboplatin AUC 6 IV/30 min
q 21 days for a total of 2 cycles
Paclitaxel 50 mg/m
2
IV/1h/week
Carboplatin AUC 2 IV/30 min/wk
XRT 6600 cGy (total) (d 43)
Vokes EE, et al. J Clin Oncol. 2007;25