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FOR EXPERT REVIEW PANEL USE ONLY

NOT FOR DISTRIBUTION

3

However, there are data shown that the conversion between the previtamin D and vitamin D is a slow

process. One report showed that at 60oC the equilibrium time was 12 hours, and at 80oC the equilibrium

time was 2.4 hours.

The saponification conditions and time ini this method seem can not ensure a equilibrium between the

previtamin D and vitamin D is established.

Recommendation: Need more investigation on the previtamin D determination.

VitD-18 Review Forms