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Radiotherapy schedules

Radical

64Gy in 32# over 6.5 weeks

55Gy in 20# over 4 weeks

High dose palliative

30-36Gy in 5-6# over 5-6 weeks

James ND et al: Radiotherapy with or without chemotherapy in muscle-invasive bladder cancer. N Engl J Med 2012,

366(16):1477-1488.

Hoskin PJ et al., Radiotherapy with concurrent carbogen and nicotinamide in bladder carcinoma. J Clin Oncol 2010, 28(33):4912-

4918. Duchesne GM et al., A randomized trial of hypofractionated schedules of palliative radiotherapy in the management of

bladder carcinoma: results of medical research council trial BA09. Int J Radiat Oncol Biol Phys 2000, 47(2):379-388