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Adaptive planning-rectal model
Nijkamp J, Marijnen C, van Herk M, van Triest B, Sonke JJ: Adaptive radiotherapy for long course neo-adjuvant
treatment of rectal cancer.
Radiother Oncol
2012, 103(3):353-359.
.
-28 patients
-
Repeat CT scans were taken daily during 1
st
week f/b once
weekly
-Substantial systematic and random shape variation
demanded for a PTV margin up to
2.4 cm
at the
upper-
anterior part
of the CTV. Plan adaptation after
fraction 4
resulted in a maximum
0.7 cm margin reduction
and a
significant PTV reduction from
1185 to 1023 cc