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EMbrace clinical trial
• European study on MRI-guided brachytherapy in locally
advanced cervical cancer
• Multi-centre observational study to introduce MRI based 3D
brachytherapy planning in 27 centres
• Collect data on outcomes and develop prognostic /
predictive markers with > 1200 patients recruited end 2014
• EMBRACE II opening with many more centres aiming to
participate
• ICRU 89: New recommendations for gynaecological
brachytherapy published 2016
• Higher dose to HR CTV improves control >85Gy
• Need to use interstitial needles in larger tumours
• Lower doses in smaller tumours