Pre-plan generated using TRUS dataset
• CTV = prostate + 3mm margin constrained by rectum
posteriorly (CTV=PTV)
• Typical planning objectives and constraints for I-125
– minimum peripheral dose of 145 Gy to CTV
– V
CTV
100 (CTV covered by 100% of the prescription dose) ≥ 95%
– D90 (dose to 90% of the CTV) > 100%
– V
CTV
150 (CTV covered by 150% of the prescription dose) < 50%
– Rectal mucosal volume which receives 100% (Vr100) of the dose of
less than 2 cc
– D
urethra
10 < 150% and D
urethra
30 < 130%
From: Tumour and target volumes in permanent prostate brachytherapy: A
supplement to the ESTRO/EAU/EORTC recommendations on prostate
brachytherapy. Salembier et al. RO 83(2007):3-10.