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Pre-plan generated using TRUS dataset

• CTV = prostate + 3mm margin constrained by rectum

posteriorly (CTV=PTV)

• Typical planning objectives and constraints for I-125

– minimum peripheral dose of 145 Gy to CTV

– V

CTV

100 (CTV covered by 100% of the prescription dose) ≥ 95%

– D90 (dose to 90% of the CTV) > 100%

– V

CTV

150 (CTV covered by 150% of the prescription dose) < 50%

– Rectal mucosal volume which receives 100% (Vr100) of the dose of

less than 2 cc

– D

urethra

10 < 150% and D

urethra

30 < 130%

From: Tumour and target volumes in permanent prostate brachytherapy: A

supplement to the ESTRO/EAU/EORTC recommendations on prostate

brachytherapy. Salembier et al. RO 83(2007):3-10.