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Metrics for volumetric comparisons

Parameter

Formula Interpretation

Ratio PET/CT

GTV

PET

/GTV

CT

Ratio CT/PET

GTV

CT

/GTV

PET

Discrepancy index (DI)

EV/OV = 1 Perfect concordance

= ∞ Complete disagreement

Conformity index (CI)

OV/EV = 1 Perfect conformity

= 0 Complete disconformity

Overlap

Fraction (OF)

or “coverage”

OF

CT

OV /GTV

CT

Proportion of GTV

CT

covered by

GTV

PET

OF

PET

OV /GTV

PET

Proportion of GTV

PET

covered by

GTV

CT

Mismatch

Fraction

(MF)

MF

CT/PET

1 - OF

CT

Volume enclosed by GTV

CT

but

not by GTV

PET

relative to GTV

CT

MF

PET/CT

1 - OF

PET

Volume enclosed by GTV

PET

but

not by GTV

CT

relative to GTV

PET

GTV

PET

GTV

CT

OV = GTV

PET

GTV

CT

EV = GTV

PET

GTV

CT

Intersection

Conjunction