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CTV margin determination-surgical experience
Examples
Lung
Grills IS, Fitch DL, Goldstein NS, Yan D, Chmielewski GW, Welsh RJ, Kestin LL: Clinicopathologic analysis of
microscopic extension in lung adenocarcinoma: defining clinical target volume for radiotherapy. Int J Radiat Oncol
Biol Phys 2007, 69(2):334-341.
• 35 patients with T1N0 NSCLC
underwent wedge resection plus
immediate lobectomy.
• GTV and microscopic extension
distance beyond the gross tumor
were measured.
• Grade analyzed for association
with microscopic extension.