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Clinically relevant?
Applications
Examples
I. Coverage of
concave
PTV with better sparing of
OAR
prostate (rectum), head
neck (spinal cord), pelvis
II. Better coverage of tumors
near critical structures
(also convex)
nasopharyngeal, prostate,
head-neck cancer,…
III. Intentionally
inhomogeneous
dose distributions
SIB, multiple GTV/CTVs...
IV. Re-irradiation
of locally recurrent tumors
spine, head-neck,…
V. Compensation
of plans
brachytherapy
13
Steep dose gradient
Conformality
Homogeneity
Potential of IMRT
→
delivery of conventional doses with
↓
toxicity
→
delivery of higher doses without
↑
toxicity