655 / 1542
Craniospinal irradiation
Medulloblastoma
• Primitive neuro-ectodermal tumour which arises most commonly in the
cerebellum
• Most common primary CNS tumour in children (20%) but uncommon in
adults (0.5 cases per 100,000)
• Most commonly arises in the posterior fossa
– Spread commonly in craniospinal axis
– Systemic metastasis is uncommon but reported
– Presenting symptoms:
Hydrocephalus related symptoms
Cerebellar symptoms
Leptomeningeal symptoms