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Tomotherapy has greater flexibility of shaping dose in axial slices than

both standard IMRT and VMAT: full IMRT per beam direction,

and beams can come from all co-planar directions

Tomotherapy may in longitudinal direction be more restricted because of field

width, if w=1cm

longer treatment times

Tomotherapy and VMAT have larger spreading of low doses over large

volumes than standard IMRT

In contrast with standard IMRT, Tomotherapy and VMAT do not require

selection of limited number of optimal beam directions

For simple cases, VMAT seems substantially faster than standard

IMRT with comparable plan quality for PTV and OAR (but spreading)

In complex cases, single-arc VMAT with short treatment times may

compromise quality of the dose distribution.

Only standard IMRT allows “free” use of non-coplanar beams

Comparison of competing techniques

Standard IMRT, Tomotherapy, VMAT

Bortfeld and Webb, 2009