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Functional imaging to assist volume definition
Advantages- Proposed individualisation
• Alternative tracers
• Hypoxic tumour regions demonstrate intrinsic radio-resistance,
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Cu-ATSM (sub-volume for dose escalation)
• ‘dose painting by contours’
• PET based volume is treated to a specified dose level while
keeping the mean dose to the remaining target constant
• ‘dose painting by numbers’
• an inhomogeneous dose across the target volume is informed by
the PET voxel intensity