Photons
p
+
, C
6+
Exponential dose fall off after build up Inverse dose profile with a maximum
energy deposition in the Bragg Peak
→
Dose at depth (target) is greater than
dose at surface
→
Steep distal dose fall off (they stop)
Reference radiation RBE
RBE > 1
Particle Therapy - Rational
1) Superior physical dose deposition properties
2) Higher relative biological effectiveness (RBE)