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Can there be a good surrogate for the

position of a lung/liver tumour?

No surrogate is so good that you can avoid IGRT

Solution 1: use large margins ( approx equal to free breathing)

Starkschall et al IJROBP 2011:

treatment using

methods designed to mitigate the effects of

respiratory motion (breath hold or gating) with

setup based on landmarks other than the actual

tumour position requires margin of 0.7 to 0.8 cm