858 / 1694
RTOG 0617 – Dose escalation
60 Gy
74 Gy
25.1%
34.4%
03/01/13
Local failure rate at 18 months post-treatment:
Does this make sense?
Reasons?
Bradley et al.,
Lancet Oncology
2015
Minimum margin was smaller in the high-dose group (mean 4·5 mm [2·9] in the
standard-dose group
vs 3·9 mm [3·0] in the high-dose group; p=0·0047)