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Author Patients (n) Marker
Results
Wong
58
p53
reduced local control and DFS
Allal
98
Bcl2, M30
Bcl2: improved local control and DFS
M30: reduced local control and DFS
Ajani
30
NF-
κ
B reduced DFS
Prognostic Relevance of Apoptosis-related
Markers
Fraunholz
62
Survivin reduced DMFS and OS
Rödel
95
pCaspase 8
improved local and distant control, CSS
and OS
Prognostic relevance of apoptosis-related
markers still controversial
Rödel 2016 submitted; Fraunholz I, Radiat Oncol 2012, Allal AS, Clin Cancer Res 2003; Ajani JA, Dig Dis Sci 2010;
Wong CS, Int J Radiat Oncol Biol Phys 1999