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TRG : WHICH IS BEST ?
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Trakarnsarga et al ( 2014 )
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563 rectal cancers : cT3/4 or N+ : 1998 – 2007
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CRT : 50.4 Gy plus 5FU based chemotherapy
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TME after 6 – 8 weeks
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Median F.U. 39 months
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pCR = 21 % ; LR = 2 %; DM = 17 %
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TRG determined by expert GI pathologists
Mandard ( 5 & 3 tier )
Dworak / Rodel ( 5 & 3 tier )
MSKCC
AJCC / CAP