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IMRT (vs 3DCRT)

- Evidence that IMRT reduces toxicity

compared to 3DCRT

- Reduction of treatment breaks

- Institutional series & Phase II

studies

(Salama 2007, Tsai 2006, Meyer

2008, Pepek 2010, Bazan 2011, Kachnic

2013, Janssen 2014)

Bazan 2011

Kachnic 2013

(RTOG0529: 45Gy

elective nodes; 50.4-54

GTV + 5FU/MMC)