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Skin and external genitalia

Common toxicity in anal RT

superficial target:

All patients experience a skin tox

moist desquamation up to 45% (3D-RT)

Influencing factors: obesity, cigarettes, chronic sun exposure

Onset at the 2° wk of RT peak in the last 2 wks

disappear 4-5 wks after RT

Treatment breaks

increased OTT

decreased RT effect