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Plan Library vs. Online Re-Planning

Plan library

Online re-planning

Does not require full segmentation of target

volumes and organs at risk

Requires full segmentation (and approval) of

target volumes and organs at risk

No time is lost by online (re)optimization of the

plan of the day

If (re)optimization time is too long intra-fractional

motion will limit the precision of online adaptive

approaches

Plan library approaches can be incorporated in

existing radiotherapy workflows

Daily (re)optimization requires a completely new

workflow

Plans stored in the plan library can be QA’d in

advance

(Re)optimized plans should be QA’d on the fly

A-priori generated treatment plans do not

necessarily accommodate all anatomies

Full (re)optimization will provide the most tight-

fitting treatment plan

Tumor shrinkage is difficult to model a-priori and

is therefore hard to incorporate in plan libraries

(Re)optimization can incorporate tumor

shrinkage, but is it safe?