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Biophysics: modeling
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Aim at:
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Understanding mechanisms
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A fitted model:
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will improve use of current treatments
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Understanding a mechanism could:
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change modeling approaches
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treatments
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impact other medical disciplines
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True multi-disciplinarity (Epidemiology, Biology,
Radiology, Other medical disciplines, …)
Heart-Lung work:
- Calls for changes in optimization of thoracic RT (consider heart dose)
- Identified new, serious, toxicity: Pulmonary hypertension
- Yielded the 1
st
animal model for human pulmonary arterial hypertension