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Major trends and research opportunities in predictive

modelling with relevant contribution from MP: Tumor

Including pre-RT (omic)

individual characteristics on

T response (

radiomic

,

genomic, proteinomic,

metabolomic,…) in predictive

models

Incorporation of individual

response (volume and

functional characteristics) by

imaging during/after RT

T progression, angiogenesis,

resistance mechanisms…

Interaction with drugs/agents

Damage and repair

mechanisms in ablative RT

and heavy Hypo

Heavy particles

Clinical trials exploring

individualized strategies for

dose prescription

Pre-clinical (mouse) models

Interaction immune response

and RT