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N. Bassler, O. Jäkel, et. al., Acta

Oncologica 49 (2010), 1170

Is Carbon really high LET?

• The larger the PTV, the lower the average LET

• With SFUD, the highest LET is always at the

distal end, i.e. in normal tissue

Optimize boost volumes for high LET

Use LET as additional degree of freedom