LATE EFFECTS: PROGNOSTICATORS
•
Radiotherapeutical management
•
Total dose
•
Fractionation
•
Target volume
•
Technology
•
Individual status:
•
Genetic predisposition (ex. Li Fraumeni)
•
Individual sensitivity
•
Patient’s age
•
Gender
•
Tumor expansion, hydrocephalus
•
Combined therapy
•
Chemotherapy (ex. cisplatin
→
ototoxicity)
•
Surgery (ex. Hypothalamic resection
→
appetite disorders, obesity)