PROGNOSTICATORS
TOTAL DOSE
•
Total dose (Whole brain, Cr Spinal)
•
25 (24) vs 35 (36) Gy : FSIQ : 12
points gain
(Silber, JCO 1992)
•
IQ < 75: 30% vs 65%
(Kieffer-Renaux, Developmental Medicine &
Child Neurolog, 2000)
•
18 vs 24 Gy IQ : 8 points gain