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PROGNOSTICATORS

TOTAL DOSE

Total dose (Whole brain, Cr Spinal)

25 (24) vs 35 (36) Gy : FSIQ : 12

points gain

(Silber, JCO 1992)

IQ < 75: 30% vs 65%

(Kieffer-Renaux, Developmental Medicine &

Child Neurolog, 2000)

18 vs 24 Gy IQ : 8 points gain