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Number

1y

3y

5y

Reirradiation

47

87.6% 71.2% 29.5%

Primary

70.4GyE)

22

77.3% 43.8% 21.5%

Reirradiation

(n=47)

Primary

(70.4GyE)

(n=22)

Author

Year

N

Total Dose

ToxicityG3

5y-Survival

Local Control

Modiuddin M 2002

34

70-108Gy

(85.8Gy)

Acute 4%

Late 26%

Surg 22%

44%

69

15%

Das P

2010

18

64-109Gy(86Gy)

Acute 4%

Late 26%

Surg 44%

32

12%

NIRS

2014 47

90-140GyE

(118GyE)

Acute 17%

Late 25% 30% 81% (5y)

Overall Survival Curves of locally recurrent rectal cancer

by primary CIRT and CIRT as reirradiation

S

u

r

vi

v

a

l

R

a

t

e

s

(

%

)