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Cranio-Spinal acute hemato. toxicity:

Pr vs XR

Protons = Be+er hematological &

diges5ve tolerance

Protons at F Up=

lesser

intensity hematological

altera<ons

Med age: 10Y (2-18)

Historical comparison

Mid Fup: 22 m

30 P+ (32 GyE) pts

vs

15 XR (29 Gy)

(Song, Acta Oncol, 2014)